Background:

Thyroid disorders are among the most prevalent endocrine diseases worldwide, affecting metabolism, growth, development, and overall physiological functions. Hypothyroidism and hyperthyroidism are the most common manifestations of thyroid imbalance. Biochemic therapy, introduced by Schussler, is based on the concept that disturbances in cellular mineral balance contribute to disease processes. The twelve tissue salts are believed to restore cellular function and support physiological balance.

Objective:

To review the therapeutic scope of the twelve tissue salts in the management of thyroid imbalance and discuss their role in supporting thyroid function from a biochemic perspective.

Method:

A narrative review of classical biochemic literature, homoeopathic Materia medica, and contemporary endocrine references was conducted. The indications of individual tissue salts relevant to thyroid dysfunction were analysed and correlated with clinical manifestations of hypothyroidism and hyperthyroidism.

Conclusion:

The twelve tissue salts may provide supportive therapeutic benefits in thyroid imbalance by addressing cellular mineral deficiencies and functional disturbances. Remedies such as Calcarean fluoric, Calcarean phosphoric, Kali phosphonium, Natrum muriaticum, and Silica is relevant to thyroid disorders. Further clinical studies are needed to establish their efficacy through evidence-based research.