NEP 2020 encourages technology-enabled skill-based student-centred learning, and constructivism-based approaches are directly aligned with these goals. Traditional mathematics education requires transformation because teaching methods often emphasise memorisation, systematic practice and examination-oriented learning, which fail to develop deep conceptual understanding or real-life problem-solving skills. The paper attempts to make student learning personalised, interactive, and data-driven by applying artificial intelligence within each level of the 5E instructional model to enhance students’ conceptual understanding and problem-solving skills in order to enable students to apply mathematical knowledge in a meaningful way.  The article also attempts to provide a clear structured explanation of how the 5E model (Engage-Explore-Explain-Elaborate-Evaluate) can be applied in the classroom in mathematics and artificial intelligence (AI) integrated learning. It will be helpful for a skilled teacher to prepare learning designing and classroom teaching.