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International Journal of Contemporary Research in Multidisciplinary

International Journal of Contemporary Research In Multidisciplinary, 2025;4(1):89-93

Impacts of Hypoxia on Blood Pressure and Heart Rate in Covid-19 Patients

Author Name: Hadi Saifullah;   Hadi Naqeebullah;  

1. Department of Internal Medicine, Nangarhar University Teaching Hospital, Jalalabad City, Nangarhar Province, Afghanistan

2. Department of Surgery, Nangarhar University Teaching Hospital, Jalalabad City, Nangarhar Province, Afghanistan

Abstract

Background: Oxygen concentration is the percentage of hemoglobin in the blood that is saturated with oxygen. The oxygen saturation in the blood is measured by a pulse oximeter, which is measured from the finger or ear lobe. The normal amount of oxygen in the blood is from 95% to 100%. If the oxygen saturation of the blood decreases from 90%, it is called hypoxia. This means that the tissues of the body do not have enough oxygen and need treatment. It consists of respiratory diseases and high altitudes. Blood pressure, pulse rate, and PsO2 are three different medical metrics that are typically used to assess a person's condition. these are still strongly associated with the heart. In this article, our goal is the relationship between hypoxia and high blood pressure and pulse rate. Methodology: This cross-sectional study was carried out in the internal medicine ward of Nangarhar University's Teaching Hospital between January and December of 2023. Samples from 2191 patients suspected of having COVID-19 were gathered by the Nangarhar University Teaching Hospital's Surveillance Supportive Team (SST), and the virus was confirmed using Polymerase Chain Reaction (PCR) and Rapid Diagnostic Test (RDT). In this hospital, these tests were performed at no cost. 1518 individuals in this group tested negative for COVID-19, while 834 cases tested positive. Out of the 834 people who tested positive for COVID-19, The hospital accepted 101 patients with arterial oxygen concentrations below 90%.and we assessed the correlation between hypoxia, hypertension, and pulse rate in 101 hypoxic individuals. A sphygmomanometer was used to monitor arterial pressure, and a pulse oximeter was used to measure oxygen saturation. All 101 hypoxic COVID-19 positives with arterial oxygen saturation below 90% were included in this investigation. Additionally, hypoxia in patients with COPD, respiratory failure, and pneumonia who did not have COVID-19 was not included. Additionally, all patients, both male and female, who were over the age of eighteen and had a connection to internal medicine were included. PsO2 was the independent variable in this study, whereas blood pressure and pulse rate were the dependent variables. Statistics Calculator, SPSS, and Excel were used to analyze the data. Multiple linear regression, which characterizes the connection between a dependent and an independent variable, is how we test the independent and dependent variables in statistics. Results: from 2191 individuals, samples were taken due to COVID-19, of which 610 were men and 1518 were women, of which 834 (38.06%) were positive for COVID-19 and 1357 (61.95%) were negative for COVID-19.346 (41.46%) were positive for COVID-19 by polymerase chain reaction (PCR), of which 118 (14.14%) were male and 228 (27.33%) were female. And 488 (58.51%) were positive for Covid-19 by Rapid Diagnostic Test (RDT), of which 176 (21.10%) males were positive for Covid-19 and 312 (81.25%) were females for Covid-19. Among the 834 patients who tested positive for COVID-19, 101 (12.11%) had hypoxia and were admitted to the internal medical of the university teaching hospital.101 patients who had hypoxia and oxygen saturation was less than 90% participated, and we found a relationship between hypoxia and heart rate and blood pressure. The minimum age of the patients was 29 and the maximum age was 90 years. Mean confidence interval 95% CI {58.3737, 63.9828}. The standard deviation (14.2066) mean was 61.1782. Mode was 70 years. 69.30% were female and 30.69% were male. the efficiency of multiple correlation (R) equals 0.185325. This means that there is a very weak correlation between the predicted data (Y1) and the observed data(Y).

Keywords

Arterial Oxygen Saturation, Blood Pressure, Hypoxia, Pulse Rate